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This decline has far-reaching effects and is linked to many of the changes we associate with ageing, such as: Persistent fatigue and reduced physical endurance Slower metabolism and increased difficulty maintaining a healthy weight Greater vulnerability to neurodegenerative conditions A less responsive, ageing immune system Declining mitochondrial health and cellular energy Its not just about energy, NAD+ supports essential cellular functions that underpin resilience, repair, and healthy ageing at every level of the body